To understand the status of Theory of Evolution, highly multidisciplinary approaches are needed. Thus, the book moves from the historical and philosophical roots, to follow a long and winding road, passing from anthropology, to linguistics, genetics, developmental biology, neuroscience, cognitive studies, to find a final lap on today theories. The inescapable conclusion, quoting the contribution of the philosopher Michael Ruse, is "that in fifty years or a hundred years we will still have the theory of the Origin around. Great, precisely because it does not stand still, but remakes itself and grows and changes by virtue of the fact that it gives such a terrific foundation. Is Darwinism past its sell-by date? Not by a long chalk yet!"